Their “fear of missing out” will be targeted after the Department for Transport said 62 per cent of drink-drivers who die in collisions were young men.
The department”s research found that 20% of young men had driven after having two or more drinks, despite this doubling their chances of being involved in a fatality.
A new advert will be released every day on Facebook, Twitter and Spotify during the month-long THINK! campaign launched on Thursday.
Road safety minister Andrew Jones said the crime, which kills five people every week, “destroys families and ruins lives”.
“This Christmas we are specifically targeting the biggest perpetrators of this devastating crime – young men. But our message to everyone remains the same: don”t drink and drive,” he said.
The campaign coincides with a month-long police operation to combat drink and drug driving during the festive period.
Forces around the country will target known hotspots to detect people who are on the road illegally.
In December last year police forces administered 110,226 breath tests, of which 5,543 were positive, failed or refused, according to the National Police Chiefs” Council (NPCC).
Some 1,888 drug screening tests were conducted during the same period, with almost half turning out positive.
The Government has also teamed up with Coca-Cola to offer two-for-one soft drinks to motorists in 8,000 pubs across the country in a bid to encourage designated drivers.
Research by price comparison website MoneySavingExpert found that for the second year running Crewe has the highest proportion of motorists with drink or drug driving convictions.
The Cheshire town has a rate of 1.66 convictions per 1,000 drivers, according to the study.
Llandrindod Wells, Powys, was ranked second, followed by Hereford in third.
London dominated the list of postcodes with the lowest conviction rates, with the north west of the capital having just 0.53 drink or drug drivers per 1,000.
The figures were based on 9.8 million car insurance quotes over the last 12 months.