They predicted that rising temperatures and rainfall will let vineyards thrive as far north as Elgin near Inverness.
The study by University College London raises the prospect of wines growing moving from Medoc to the Medway, Sancerre to Sandringham and Spumante to Spennymoor.
English wine producers have been winning plaudits and top international prizes in recent years – including for fizz.
The report, commissioned by Laithwaite’s Wine, said large areas of the country – including Essex, the East of England and Edinburgh – could become leading wine producing regions by 2100.
Laithwaite’s produced a Wine Growing Regions map of Great Britain in 2100 showing Edinburgh and the Borders producing Riesling, Pinot Noir and Pinot Grigio.
While the Tyne Valley will rival the Loire Valley with its Chardonnay, Riesling and Pinot Noir.
Britain has already experienced rising temperature and rainfall through climate change.
Temperatures are expected to increase by at least a further 2.2C by 2100 and rainfall will rise by 5.6 per cent.
This will transform Britain from a marginal, cool climate to an intermediate climate.
Professor Mark Maslin from University College London said: “Climate is critical to successful grape cultivation.
“This study could signal how we think long-term about British wine production and redraw the future wine map of the world.
“However, exactly where would be best for particular grapes will depend on site, slope, aspect, soil and drainage – as wine making is much an art as it is a science.”
The climate is expected to warm sufficiently to allow Malbec – Argentina’s classic red – to be grown in the Thames Estuary in Southend and Romford.
The Severn Pocket around Bristol will be perfect for Merlot and the industrial Black Country could become wine country by growing Chardonnay, Riesling, Pinot Noir and Sauvignon Blanc.
And a microclimate around Elgin east of Inverness is expected to allow Pinot Grigio to be cultivated.
Davy Zyw of Laithwaite’s Wine added: “It’s not long ago that experts scoffed at the idea of English, let alone wider British wine.
Now thanks to a changing climate, as well as passion and expertise, we could see wine buyers from all over the world coming to taste the latest UK vintages in a few generations.”
The scale of the renaissance in English wine can be seen in figures released by The Wine and Spirit Trade Association.
In the last decade the area of planted vines in England and Wales has more than doubled and is expected to grow by another 50 per cent by 2020.
Since 2011 the number of bottles produced here has risen from 3 million to more than five million – but most of the 5,000 acres of vineyards are currently in Kent, Sussex and Hampshire.